赢创和利卡特在羰基化领域取得突破性进展

据烃加工在线1月6日报道，赢创（Evonik）公司领导的研究团队在羰基化领域取得了突破性进展。羰基化反应是化学工业最重要的反应类型之一，涉及将一个

-CO-（羰基）催化引入到有机化合物中。六十多年来，科学界与工业界一直在寻找一种切实有效方法来实施这一过程，目前终于成功实现。

由德国罗斯托克莱布尼兹催化研究所（Leibniz Institute for Catalysis, Rostock）所长Matthias Beller博士和赢创性能材料有限公司Robert Franke博士领导的研究小组成功地使原料1,3-丁二烯发生了双羰基化反应，直接生产己二酸脂。而目前己二酸酯只能通过复杂的多段、高能耗和高成本的方法来合成，不仅要使用多种化学物质，还将释放温室气体氮氧化物（NOx）。

己二酸酯通常作为生产多种产品的原料，如增塑剂、香水、润滑剂、溶剂、各种活性药物成分，尤其是尼龙等，全球每年己二酸酯的产量达到数百万吨，所以该项创新的潜在益处是巨大的。

该项目参与者开发的新工艺，提供了更环保、更具有成本效益的合成方法。

特定膦配体（HeMaRaPhos）新型钯催化剂的开发是该项目的关键技术。该配体与钯结合，制备出一种高选择性、高效、长寿命的催化剂，在工业上条件下可使己二酸衍生物的产率高达95%。

贾丽 摘译自 烃加工在线

原文如下：

Evonik and LIKAT achieve breakthrough in carbonylation chemistry

A research team with leading participation of Evonik has achieved a breakthrough in the field of carbonylation chemistry. Carbonylation is one of the most important types of reaction in the chemical industry. It involves the catalyzed introduction of a CO group (carbonyl group) into organic compounds. For more than 60 years, science and industry had been looking for a way to implement the now successful reaction step.

A team was led by Prof. Dr. Matthias Beller, Director of the Leibniz Institute for Catalysis, Rostock, and Prof. Dr. Robert Franke, Evonik Performance Materials GmbH. The scientists have succeeded in double carbonylating the starting material 1,3-butadiene directly to produce adipates. Adipates can currently only be produced by a complex multi-stage, energy- and cost-intensive synthesis. This involves not only the use of many chemicals, but also releases climate-relevant nitrogen oxides (NOx), which are among the main greenhouse gases.

The potential benefits from this innovation are great: adipates are produced annually on a large scale in the millions of tonnes and serve as starting materials for the manufacture of numerous products such as plasticizers, perfumes, lubricants, solvents, various active pharmaceutical ingredients and above all nylon.

With their new process, the participating project partners are laying the foundation for a more environmentally friendly and cost-effective large-scale method of synthesis.

The key to the breakthrough Development of a new palladium catalyst based on a specific phosphine ligand (HeMaRaPhos). This ligand binds to palladium, resulting in a highly selective, efficient and long-lived catalyst that can result in 95% yields of adipic acid derivatives under industrially feasible conditions.